The Patient-Specific Artificial Respiratory Unit (PARU) is an advanced simulation platform designed for personalized respiratory management training. It replicates individual lung mechanics, enabling realistic procedural practice for conditions such as acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and respiratory failure. PARU features a patient-specific respiratory system design, simulating lung compliance, resistance, and tidal volume, allowing clinicians to practice ventilation management using real ventilators. This supports hands-on training in intubation, mechanical ventilation adjustments, and respiratory therapy protocols with lifelike feedback. The system supports multi-level training, accommodating beginners learning respiratory basics and advanced practitioners performing complex procedures like extracorporeal membrane oxygenation (ECMO). Its modular design ensures seamless integration into clinical workshops, training labs, and classrooms. With real-time feedback on respiratory parameters, PARU enhances clinical decision-making by allowing users to adjust treatments and visualize outcomes. This interactive learning experience strengthens procedural skills while reducing real-life intervention risks. In summary, PARU offers a comprehensive, high-fidelity respiratory training solution, combining patient-specific simulation, advanced respiratory mechanics, and interactive feedback to improve clinical proficiency, enhance patient safety, and advance respiratory care education