Aptamer for Detecting Acinetobacter baumannii

Aptanova (Universiti Malaya)
Socio-Economics Driver
Medical & Healthcare
Science & Technology Driver
Bioscience Technology
Technology Readiness Level
6
Intellectual Property
PI 2024007376

This solution stands out by combining rapid aptamer-based precision detection with targeted bacterial neutralization in a single integrated platform. Unlike conventional culture-based diagnostics that require long processing times, this technology enables on-site identification within minutes, significantly reducing treatment delays. Additionally, its smart disinfectant approach specifically targets Acinetobacter baumannii rather than relying solely on broad-spectrum chemical disinfectants, improving efficiency and infection control outcomes. The patent-protected aptamer technology and consumables-driven business model further strengthen its scalability and defensibility in the hospital diagnostics market.

Hospital-acquired infections (HAIs), particularly those caused by Acinetobacter baumannii, pose a serious threat to patient safety, especially in ICUs and surgical units. According to WHO data, 1 in 10 hospitalized patients in developing countries acquires an infection, and delays in effective treatment significantly increase mortality risk. Current bacterial detection methods are time-consuming, causing delays in diagnosis and treatment. Hospitals also struggle with persistent, drug-resistant pathogens that survive conventional disinfectants. Therefore, there is an urgent need for rapid, precise detection and targeted elimination of dangerous bacteria directly on-site.

The solution uses a patented aptamer that specifically binds to Acinetobacter baumannii. Aptamers function like “smart glue,” recognizing and attaching to the target bacteria with high precision. This enables rapid diagnostic kits that can instantly identify harmful bacteria within minutes. In addition, the same targeting mechanism is used in smart disinfectants that seek out and neutralize stubborn pathogens effectively. The dual approach allows both detection and destruction of the bacteria in clinical environments.

The innovation lies in using aptamer technology for both rapid detection and targeted elimination of drug-resistant bacteria such as Acinetobacter baumannii. This dual-function approach enables faster diagnosis and precise disinfection, improving infection control in healthcare settings.

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